TIMI score = Thrombolysis in Myocardial Infarction score. It is a validated risk score. The TIMI score was initially validated as a prognostic tool for patients admitted for ACS but has been studied for use in the diagnosis of MI.
TIMI Risk Score for UA/NSTEMI
Estimates risk at 14 days of all-cause mortality, new or recurrent MI, or severe recurrent ischemia requiring urgent revascularization for patients with unstable angina and non-ST elevation MI.
The TIMI Score was developed in AMERICA to predict adverse outcomes in patients with UA and NSTEMI. The TIMI risk score is composed of seven independent risk factors:
Age ≥ 65 years,
Markers (elevated cardiac markers)
ECG (ST-segment depression at presentation)
Risk Factors (3 or more cardiovascular risk factors)
Ischemic chest pain (at least 2 or more anginal events in the previous 24hrs)
Coronary stenosis (prior stenosis of 50% or more)
Aspirin (aspirin usage in the past 7 days)
This simple prognostication tool from the USA can be remembered by the mnemonic, AMERICA.
Risk factors include:
- Hypercholesterolemia
- Hypertension
- Diabetes Mellitus
- Cigarette smoking
- Positive family history
- Obesity