Statin Use for Primary Prevention of ASCVD, USPSTF Recommendations.
The 2013 ACC/AHA cholesterol guidelines
According to the ACC/AHA, there are 4 major groups are in whom statin therapy is indicated:
(1) individuals with clinical atherosclerotic cardiovascular disease (ASCVD),
(2) those with primary elevations of LDL-C >190 mg/dL,
(3) patients age 40–75 with diabetes mellitus, an LDL-C level of 70–189 mg/dL, and no clinical ASCVD,
(4) patients age 40–75 without clinical ASCVD or diabetes, an LDL-C level of 70–189 mg/dL, and an estimated 10-year ASCVD risk >7.5%.
For patients who are age 40–75 with diabetes, an LDL-C level of 70–189 mg/dL, and no clinical ASCVD, a moderate-intensity statin is recommended.
Further Reading / Reference
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. Circulation 2014;129(25 Suppl 2):S1-S45. https://www.ncbi.nlm.nih.gov/pubmed/24222016