Definition of MI

CARDIOLOGY

An MI is defined as a cardiac troponin (I or T) level above the 99th percentile of a normal reference population, plus one or more of the following:

  1. Symptoms of ischemia
  2. New significant ST/T wave changes or left bundle branch block (LBBB)
  3. Pathologic Q waves on ECG
  4. New loss of viable myocardium or regional wall motion abnormality, as observed on imaging
  5. Intracoronary thrombus diagnosed by angiography or autopsy

Reference

Jneid H, Alam M, Virani SS, Bozkurt B. Redefining Myocardial Infarction: What Is New In The ESC/ACCF/AHA/WHF Third Universal Definition Of Myocardial Infarction? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782325/

Skeik N, Patel DC. A review of troponins in ischemic heart disease and other conditions. The International Journal of Angiology : Official Publication of the International College of Angiology, Inc. 2007;16(2):53-58.

Daubert MA, Jeremias A. The utility of troponin measurement to detect myocardial infarction: review of the current findings. Vascular Health and Risk Management. 2010;6:691-699.

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