Dosage for prevention Dosage for treatment
AMS
Acetazolamide 125 or 250 mg every 12 h 250 mg every 12 h
Dexamethasone 2 mg every 6 h OR
4 mg every 12 h
4 mg every 6 h
HACE
Dexamethasone 8 mg once then 4 mg every 6 h
HAPE    
Nifedipine 30 mg sustained release version every 12 h 30 mg sustained release version every 12 h
Tadalafil# 10 mg every 12 h 10 mg every 12 h
Salmeterol 125 μg inhaled every 12 h Not used for treatment

Modified from European Respiratory Review Mar 2017, 26 (143) 160096.

AMS: acute mountain sickness; HAPE: high-altitude pulmonary edema; HACE: high-altitude cerebral edema.
#: Tadalafil should not be used in conjunction with nifedipine;
: Salmeterol should not be used as the sole agent for prevention.

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