Statins do the following:
- Lowering cholesterol,
- Reduce vascular inflammation,
- Improve endothelial function, and
- Stabilize atherosclerotic plaques.
Statins are recommended for the following uses
- Vascular or coronary surgery. Reduces cardiovascular risk when given perioperatively. For the most protection, statins should be started 4 weeks prior to the procedure and continued after surgery.
- Stroke patients
- Elevated ASCVD score.
Statins decrease cardiac & overall mortality in pts with or without ASCVD.